000			02128 a2200277 4500
005			20260218124140.0
008			260214b |||||||| |||| 00| 0 eng d
020			_a9781788012096
082			_a615.19 AGR
100			_aAgrawal, Sudhir (Ed.)
245			_aAdvances in nucleic acid therapeutics
260			_aLondon: _bRoyal Society of Chemistry, _c2019.
300			_axxiv, 541p.: _bcol., ill.; hbk.: _c24cm.
440			_aDrug Discovery Series ; no. 68
504			_aInclude References and Subject Index
520			_aThe sequencing of the human genome and subsequent elucidation of the molecular pathways that are important in the pathology of disease have provided unprecedented opportunities for the development of new therapeutics. Nucleic acid-based drugs have emerged in recent years to yield extremely promising candidates for drug therapy to a wide range of diseases. Advances in Nucleic Acid Therapeutics is a comprehensive review of the latest advances in the field, covering the background of the development of nucleic acids for therapeutic purposes to the array of drug development approaches currently being pursued using antisense, RNAi, aptamer, immune modulatory and other synthetic oligonucleotides. Nucleic acid therapeutics is a field that has been continually innovating to meet the challenges of drug discovery and development; bringing contributions together from leaders at the forefront of progress, this book depicts the many approaches currently being pursued in both academia and industry. A go-to volume for medicinal chemists, Advances in Nucleic Acid Therapeutics provides a broad overview of techniques of contemporary interest in drug discovery. https://books.rsc.org/books/edited-volume/770/Advances-in-Nucleic-Acid-Therapeutics
650			_aNucleic Acid–based Therapies
650			_aAntisense Oligonucleotides
650			_aDNA and RNA Therapeutics
650			_asiRNA and mRNA Therapeutics
650			_aRNAi-Based Anti-HIV Therapeutics
650			_aImmune Modulatory
650			_aMedicinal Chemists
700			_aGait, Michael J. _eCo-editor
942			_cTD _2ddc
999			_c64076 _d64076