000			02874 a2200313 4500
008			251011b |||||||| |||| 00| 0 eng d
020			_a9781783268795
082			_a660.6 BAL
100			_aBaldwin, Geoff
245			_aSynthetic biology: a primer
260			_aSingapore: _bImperial College Press-World Scientific Publishers, _c2016.
300			_axiv, 179p.: _bcol. ill.; pbk.: _c25 cm.
504			_aIncludes Glossary and Index.
520			_aSynthetic Biology — A Primer (Revised Edition) presents an updated overview of the field of synthetic biology and the foundational concepts on which it is built. This revised edition includes new literature references, working and updated URL links, plus some new figures and text where progress in the field has been made. The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely 'bottom-up' and 'top-down' engineering approaches. 'Top-down' engineering uses a conceptual framework of systematic design and engineering principles focused around the Design-Build-Test cycle and mathematical modelling. The 'bottom-up' approach involves the design and building of synthetic protocells using basic chemical and biochemical building blocks from scratch exploring the fundamental basis of living systems. Examples of cutting-edge applications designed using synthetic biology principles are presented, including: the production of novel, microbial synthesis of pharmaceuticals and fine chemicals the design and implementation of biosensors to detect infections and environmental waste. The book also describes the Internationally Genetically Engineered Machine (iGEM) competition, which brings together students and young researchers from around the world to carry out summer projects in synthetic biology. Finally, the primer includes a chapter on the ethical, legal and societal issues surrounding synthetic biology, illustrating the integration of social sciences into synthetic biology research. Final year undergraduates, postgraduates and established researchers interested in learning about the interdisciplinary field of synthetic biology will benefit from this up-to-date primer on synthetic biology. https://www.worldscientific.com/worldscibooks/10.1142/p1060#t=aboutBook
650			_aSynthetic Biology
650			_aMolecular Biology
650			_aGenetic Engineering
650			_aMetabolic Engineering
650			_aSynthetic Genomics
650			_aBioengineering
700			_aBayer, Travis _eCo-author
700			_aDickinson, Robert _eCo-author
700			_aEllis, Tom _eCo-author
700			_aFreemont, Paul S. _eCo-author
700			_aKitney, Richard I. _eCo-author
700			_aPolizzi, Karen _eCo-author
700			_aStan, Guy-Bart _eCo-author
942			_cTD _2ddc
999			_c63201 _d63201